Silk fibroin has become a popular biomaterial due to its excellent biocompatibility, exceptional mechanical properties, tunable degradation, ease of processing, and sufficient supply. As a material with excellent processability, Silk Fibroin can be processed into various forms with different structures, including particulate, fiber, film, and three-dimensional (3D) porous scaffolds. Silk fibroin, a natural fibrous protein, is a more biocompatible biomaterial than some commonly used biological polymers such as collagen and poly(l-lactic acid) (PLA) .Reference: A Review of Structure Construction of Silk Fibroin Biomaterials from Single Structures to Multilevel Structures, Int J Mol Sci. 2017 Mar 3;18(3):237.
“Very simply, silk supports cellular infiltration and proliferation. Cells just like to go near it. And any cell type will grow into it,” says David Kaplan, Ph.D., Chair of Tufts University’s Department of Biomedical Engineering, about silk protein biomaterials.
- Silk Fibroin is a biomaterial well known for its similarity with human skin.
- It has the same aminoacid chain of our stratum corneum: glicyne 40%, alanine 25%, serine 15%, tyrosine 10%, other aminoacids 10%.
- Enhances collagen synthesis and re-epithelialization.
- Amphoteric (natural pH around 5 – 5,5).
Silk fibroin protein has unique beneficial properties for tissue regeneration. It provide and facilitates tissue ingrowth and it is biocompatible: it is an ideal cellular scaffold different from other proteins used in tissue regeneration (such as elastin, keratin, collagen and hyaluronic acid).
SILK FIBROIN WITH ANTIMICROBIAL PROTECTION AEM
· Permanently bonded to the silk fibroin fibres.
· Non-migrating, non-leaching antimicrobial.
· Mechanically interrupts the micro-organisms cell wall (by electrocution).
· Not consumed by micro-organisms.
· It maintains its effectiveness throughout the life of the product.
· Does not modify the resident skin flora.
· Does not create microbial adaptation or resistance.
· Odourless, colourless.
· Effective against a wide spectrum of microorganisms.